Sandor LifeSciences
Biosciences Research Services

Metabolomics

Metabolomics is studying of chemical processes involving metabolites. Specifically, it is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles within cells, biofluids, tissues or organisms.

This rapidly emerging field combines strategies to identify and quantify cellular metabolites using complex and sensitive analytical technologies alone with the application of the statistical and multi-variant methods for information extraction and data interpretation. Mass spectrometry coupled to different chromatographic separation techniques, such as liquid or gas chromatography or NMR, are the major tools to analyze large number of metabolites simultaneously. Due to the huge diversity of chemical structures and the large differences in abundance, there is no single technology available to analyze the entire metabolome. Therefore, a number of complementary approaches have to be established for extraction, detection, quantification and identification of metabolites.

Offered services:

  • Metabolome extraction and purification from biological specimens.
  • Metabolite derivetization and quantification on GCMS.
  • Strategies for specific metabolome quantification and differential expression by LCMSMS-ESI-QTOF analysis.
  • Bioinformatics and statistical analysis.
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